Matrix Metalloproteinase-9: Many Shades of Function in Cardiovascular Disease
نویسندگان
چکیده
منابع مشابه
Matrix metalloproteinase-9: Many shades of function in cardiovascular disease.
Matrix metalloproteinase (MMP)-9, one of the most widely investigated MMPs, regulates pathological remodeling processes that involve inflammation and fibrosis in cardiovascular disease. MMP-9 directly degrades extracellular matrix (ECM) proteins and activates cytokines and chemokines to regulate tissue remodeling. MMP-9 deletion or inhibition has proven overall beneficial in multiple animal mod...
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ژورنال
عنوان ژورنال: Physiology
سال: 2013
ISSN: 1548-9213,1548-9221
DOI: 10.1152/physiol.00029.2013